Ingredient
African Mango Seed Extract: What the Evidence Shows
African mango seed extract is a powder made from the seeds of the Irvingia gabonensis tree. In Payarmin it is the fourth of 22 lines in a 200 mg blend, so it holds at most 50 mg per 1 mL. Studies on it are small and weak, and the blood sugar findings come from rats.
Written by the Payarmin label deskUpdated
The ingredient01
What is African mango seed extract?
African mango seed extract is a supplement ingredient made from the seeds of Irvingia gabonensis, a tree of West and Central Africa. Supplement makers sell it mainly for weight and cholesterol.
The Payarmin label spells the plant "Irvingia gabonesis" with one letter dropped. It lists the ingredient as the fourth line of the proprietary blend, after maca, grape seed and guarana. The sales page also names it, as one of only six ingredients it mentions (Payarmin sales page).
Memorial Sloan Kettering sums up the research in one line: the seed extract may support weight loss, but high-quality studies are needed (MSKCC, African mango). Most of the studies are small and of poor quality.
| Name on the label | African Mango (Irvingia gabonesis) Seed Extract |
|---|---|
| What it is | Irvingia gabonensis seed |
| Place on the label | 4 of 22 in the 200 mg proprietary blend |
| Amount per 1 mL serving | Not listed; #4 of 22 in the 200 mg blend, so at most 50 mg per 1 mL, and 9 mg if all lines were equal |
| Amount used in research | No dose checked |
| Strength of evidence | Small, poor-quality weight studies; glucose evidence from rats |
| Marketed or traditional use | Seed extract marketed for weight and cholesterol |
| Main caution | Gas, headache, sleep trouble; may add to diabetes drugs; one dialysis case report. |
Which plant02
Is African mango the same as the mango fruit?
No. African mango is a different tree from the one that gives the mango fruit you eat. The supplement uses the seed, not the juicy flesh.
The Irvingia tree bears a fruit sometimes called wild mango or bush mango. The extract on a supplement label comes from the seed inside. So a label that says "African mango" does not mean you are getting mango fruit, mango flavor or mango fiber.
A fruit-style name suggests food. A seed extract is a concentrated plant product, so the cautions below apply even though the name sounds mild.
Blend math03
How much African mango seed extract is in Payarmin?
The label does not say. It gives a ceiling instead: at most 50 mg per 1 mL serving, and about 9 mg if all 22 blend lines were equal.
The reasoning is short. The blend weighs 200 mg per serving. By law the lines run from most to least by weight, with total weight shown but not single amounts (eCFR, 21 CFR 101.36). African mango is fourth. The three lines above it each weigh at least as much as it does. So four equal-or-larger lines must fit inside 200 mg, which caps this one at 200 divided by 4, or 50 mg.
That 50 mg is a ceiling from label order, not a lab result. The true amount could be far lower. Slide to line 4 to see it.
Line 12, Panax ginseng aerial extract, can hold at most 16.7 mg of the 200 mg. An even split would be 9.1 mg.
Gold: the most that line can hold. Red: what is left for the other lines. The label gives only the 200 mg total and the order (eCFR, 21 CFR 101.36); the rule is that a line cannot weigh more than the lines listed before it, so line k holds at most 200 divided by k. It is arithmetic on the label, not a lab result.
The label also does not say how much a dropper holds. If a dropper is 1 mL, a 2-dropper day would double these figures. That is an assumption, and the label does not confirm it. We found no studied dose for the extract in the source we read, so we cannot say whether 50 mg, or double that, is close to anything tested.
Weight04
Does African mango seed extract help with weight loss?
It may, but the evidence is thin. Reviews describe small studies with poor methods, so no one can say how large any effect would be.
Memorial Sloan Kettering reports that the seed extract may support weight loss and that high-quality studies are still needed (MSKCC, African mango). Systematic reviews of the trials found poor study design. Small trials with weak methods can overstate a result.
The Payarmin label makes no weight claim. Its front claims are about energy, natural ingredients and a "Balance Form System*". The sales page talks about healthy weight (Payarmin sales page), but no trial has tested Payarmin. A tiny share of one ingredient in a 22-line blend cannot be assumed to do what a full dose did in a study.
Weight is the best-studied use of this extract, and even there the sources call the evidence limited. For Payarmin, the ingredient is present, but at an unknown and probably small amount.
Payarmin: from $49 a bottle30 mL drops · 2, 3 or 6 bottles · free shipping on 3 or 6 · 60-day guarantee
See packsBlood sugar05
Does African mango affect blood sugar or cholesterol?
Cholesterol findings exist but are limited. For blood sugar, the glucose-lowering effects come from rat studies, so African mango has not been shown to lower blood sugar in people.
Memorial Sloan Kettering says the seed extract may have positive effects on obesity and cholesterol, but the data are limited (MSKCC, African mango). It lists glucose among outcomes in one randomized trial. Yet it also states that the glucose-lowering effects it cites are from rat studies.
That gap is the key point for anyone with diabetes. A rat result tells us a question is worth asking. It does not tell us what happens in a person. No trial shows Payarmin lowers blood sugar, and nothing in the African mango research changes that.
The same source warns about one real risk. Rat studies suggest African mango could add to the glucose-lowering effect of diabetes drugs. Whether that matters in people is not known (MSKCC, African mango). The source advises against combining it with antidiabetic medicines.
Do not stop or change any diabetes medicine because of a supplement. Ask your clinician before you start Payarmin, and keep checking your blood sugar as you were told. A reading under 70 mg/dL needs prompt care (NIDDK, Low blood glucose).
Safety06
Can African mango seed extract cause side effects?
Yes. Reported effects include gas, headaches and trouble sleeping. There is also one serious case report, and an interaction caution with diabetes drugs.
The source we read lists gas, headaches and difficulty sleeping (MSKCC, African mango). It describes one 42-year-old who became dialysis-dependent after about two and a half months of an African mango herbal medicine. One case report cannot prove cause, and the product was not Payarmin. It is still reason for care if you have kidney disease.
The same source says the extract may interfere with how other medicines are absorbed (MSKCC, African mango). If you take daily medicine, ask a pharmacist about timing and about this ingredient by name.
- Common reports: gas, headache and poor sleep.
- Medicine caution: may add to diabetes drugs in rats, and may change how other medicines are absorbed.
The label itself asks pregnant or nursing mothers, anyone under 18 and anyone with a known medical condition to consult a physician first. The other cautions in the drops, such as guarana and the licorice compound, are on the side effects page.
Bottom line07
Is African mango a reason to choose Payarmin?
Not by itself. The ingredient has limited evidence, and its amount in Payarmin is hidden and capped at 50 mg per 1 mL.
African mango is one of the six ingredients the sales page names, so shoppers may take it as a selling point. The label shows it is one line in 22, sharing a 200 mg blend with amino acids, herbs and a licorice compound. The full ingredient list shows every line and its ceiling.
- Fair: the ingredient is on the label, in plain view, in a set order.
- Weak: no printed amount, no studied dose we could check and no trial of the drops.
- Caution: possible additive effect with diabetes drugs, plus gas, headache and sleep trouble.
If you still want the drops, the 60-day guarantee is on the guarantee page. To see the label in full, open Payarmin supplement facts.
FAQ08
African mango seed extract questions
What is African mango seed extract?
African mango seed extract is a concentrated powder made from the seeds of the Irvingia gabonensis tree. It is sold mainly for weight and cholesterol. In Payarmin it is the fourth blend line, and the label prints no amount for it.
Which plant does African mango come from?
It comes from Irvingia gabonensis, a tree of West and Central Africa. The Payarmin label prints the name as Irvingia gabonesis. The supplement uses the seed. The tree is not the one that bears the common mango fruit.
Does African mango help with weight loss?
It may, but the evidence is weak. Memorial Sloan Kettering says the seed extract may support weight loss and that high-quality studies are needed. Most trials are small and of poor quality. No trial has tested Payarmin for weight.
Does African mango affect blood sugar or cholesterol?
Studies hint at cholesterol benefits, with limited data. The glucose-lowering effects come from rat studies, so they are not shown in people. The source also warns the extract may add to diabetes drugs. No trial shows Payarmin lowers blood sugar.
How much African mango extract is in Payarmin?
The label does not say. It lists the extract fourth in a 200 mg blend, so it holds at most 50 mg per 1 mL, by label order. The real amount may be much lower. If all 22 lines were equal, each would hold about 9 mg.
Can African mango cause side effects?
Yes. Reported effects are gas, headaches and trouble sleeping. One case report describes a person who needed dialysis after about two and a half months on an African mango herbal medicine. It may also add to diabetes drugs, so ask a clinician first.
Is African mango the same as the mango fruit?
No. The supplement uses the seed of a different tree, not the flesh of the fruit you eat. A label that says African mango does not mean mango fruit, flavor or fiber is in the bottle. It is a concentrated seed extract.
Who wrote this09
Written and reviewed by
Pages built from the label, the sales page and linked NIH, FDA, CDC, FTC and peer-reviewed sources.
Last updated . Read our editorial standards and how we check reviews. This website is run by Gopayarmin, a Payarmin U.S. shop, not by the manufacturer or the distributor. We earn money when you buy through our order links.
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