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Ingredient

Gymnema for Blood Sugar: What a Blend Line Can Hold

Quick answer

Gymnema is a leaf extract sold for blood sugar and sugar cravings. In Payarmin it is the eighth of 22 blend lines, so it holds at most 25 mg per 1 mL, and the label prints no exact amount. The usual studied dose is 400 mg three times a day. Human trials show only mild drops in fasting glucose.

Written by the Payarmin label deskUpdated

The ingredient01

What is gymnema, and what does it do in Payarmin?

Gymnema is a leaf extract from Gymnema sylvestre, a woody climbing plant. Payarmin lists it as "gymnema leaf extract", eighth of 22 lines in the 200 mg blend.

The sales page names gymnema as one of six ingredients (Payarmin sales page). Marketing links it to blood sugar and sugar cravings. The label makes no such claim. Read the "amount" row below twice: the label does not print it.

Gymnema leaf extract in Payarmin: what the label shows, next to research. Sources: (NIH LiverTox, Gymnema) (Khan 2019, Gymnema review)
Name on the labelGymnema Leaf Extract
What it isGymnema sylvestre leaf
Place on the label8 of 22 in the 200 mg proprietary blend
Amount per 1 mL servingNot listed; #8 of 22 in the 200 mg blend, so at most 25 mg per 1 mL, and 9 mg if all lines were equal
Amount used in research400 mg three times a day is the usual recommendation
Strength of evidenceMild fasting glucose drops; effect on diabetes not shown
Marketed or traditional useLeaf used for sugar cravings
Main cautionRare liver injury reports; may add to diabetes drugs.

Research02

Does gymnema lower blood sugar in people?

Only a little, and not reliably. Several human trials showed mild drops in fasting plasma glucose, but "the overall effectiveness in the treatment of diabetes has not been shown" (NIH LiverTox, Gymnema).

The strongest findings come from lab and animal work. The NIH liver database says those studies reported blood sugar lowering (NIH LiverTox, Gymnema). A 2019 review notes that "not many" clinical studies exist, and that the antidiabetic results it covers came from rodents and cell tests (Khan 2019, Gymnema review).

The NCCIH says that for most supplements there is no evidence of a beneficial effect on diabetes or its complications (NCCIH, Diabetes and supplements). The American Diabetes Association does not recommend supplements unless a deficiency is diagnosed (ADA, Vitamins and supplements).

The "regenerate" claim

The sales page says an ingredient can "regenerate" insulin-producing cells and gives no source (Payarmin sales page). The only support the review found came from rats given a chemical that damages these cells, and the authors call a leap to people speculation (Khan 2019, Gymnema review).

Blend math03

How much gymnema can one Payarmin serving hold?

At most 25 mg per 1 mL serving, because it sits eighth: 200 mg divided by 8. The real amount is lower and is not printed.

The law lets a blend show its total weight and list parts from most to least by weight, with no single amounts (eCFR, 21 CFR 101.36). If all 22 were equal, each would hold about 9 mg.

The usual recommendation is 400 mg three times a day, or 1,200 mg (NIH LiverTox, Gymnema). Even at the ceiling, one serving gives about 2% of one day's usual dose.

  • Chromium (as chromium picolinate)

    Under 4% of the lowest adequate intake
    Printed on the label, per 1 mL0.7 mcg
    Adequate intake, adult women 51+ (lowest)20 mcg
    Daily amount in a 2024 trial that found no effect1,000 mcg

    Printed: 0.7 mcg, 2% DV. (NIH ODS, Chromium)

  • Green tea leaf extract

    At most 36% of the studied amount, likely far less
    Label-order ceiling (place 7 of 22)29 mg
    Even split of the blend (all 22 equal)9.1 mg
    Catechins, 80-1,344 mg a day, in 27 trials80-1,344 mg

    Not printed: #7 in a 200 mg blend of 22. (Xu 2020, Green tea and glucose)

  • Gymnema leaf extract

    At most 2% of the studied amount, likely far less
    Label-order ceiling (place 8 of 22)25 mg
    Even split of the blend (all 22 equal)9.1 mg
    400 mg three times a day, the usual recommendation1,200 mg

    Not printed: #8 in a 200 mg blend of 22. (NIH LiverTox, Gymnema)

  • Beta-alanine

    Under 1% of the studied amount
    Label-order ceiling (place 17 of 22)12 mg
    Even split of the blend (all 22 equal)9.1 mg
    4,000-6,000 mg a day in exercise studies4,000-6,000 mg

    Not printed: #17 in a 200 mg blend of 22. (ISSN, Beta-alanine position stand)

  • L-carnitine base

    At most 4% of the studied amount, likely far less
    Label-order ceiling (place 22 of 22)9.1 mg
    Even split of the blend (all 22 equal)9.1 mg
    250-4,000 mg a day in insulin-resistance trials250-4,000 mg

    Not printed: #22 in a 200 mg blend of 22. (NIH ODS, Carnitine)

Pale bars: the most the label order allows (200 mg divided by the place). Mid bars: an even split, 9.1 mg each. Dark bars: daily amounts used in studies of that ingredient alone. The label prints none of these blend amounts, and the studies tested the ingredient by itself, not Payarmin.

The ceiling comes from label order, not from a lab result. Drag the slider to see the ceiling for any other line.

Line 12

Line 12, Panax ginseng aerial extract, can hold at most 16.7 mg of the 200 mg. An even split would be 9.1 mg.

Gold: the most that line can hold. Red: what is left for the other lines. The label gives only the 200 mg total and the order (eCFR, 21 CFR 101.36); the rule is that a line cannot weigh more than the lines listed before it, so line k holds at most 200 divided by k. It is arithmetic on the label, not a lab result.

Quality04

What is gymnema leaf extract, and how are products compared?

It is a concentrated leaf product, and strength varies a lot from one brand to the next.

The NIH notes that gymnema products are poorly standardized in purity and concentration (NIH LiverTox, Gymnema). A label that says only "gymnema leaf extract" gives no extract ratio and no amount of any active compound.

What a shopper can and cannot check for gymnema in Payarmin
QuestionWhat the label shows
Which part of the plant?Leaf
Amount per 1 mLNot published
Gymnemic acid contentNot published
Lab reportNot published

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Cravings05

Does gymnema reduce sugar cravings?

The sources we checked do not test cravings, so we cannot say yes.

The NIH page covers fasting glucose and liver safety, not appetite or taste (NIH LiverTox, Gymnema).

If cravings are your goal, habits have better support: regular activity, enough sleep and steady meals. The cravings and energy guide covers them.

Safety06

Can gymnema cause low blood sugar or liver problems?

Liver injury is rare but has been reported. Low blood sugar in people is not described as a risk in our main source, yet it is a fair question for anyone on diabetes medicine.

The NIH lists gymnema as a possible rare cause of liver injury. In the main case, a woman of 60 developed jaundice after gymnema tea, and her tests returned to normal within six months. Long-term and high-dose use in people has not been studied (NIH LiverTox, Gymnema).

Lab studies reported blood sugar lowering, and other ingredients in the blend, such as chromium and ginseng, are also said to lower it a little (MSKCC, Chromium) (NCCIH, Asian ginseng). Supplements can interact with medicines and lead to a high or low reading (ADA, Vitamins and supplements).

Keep taking prescribed medicine

Never stop or change a diabetes medicine because of a supplement. A reading under 70 mg/dL, or a faint or confused feeling, needs prompt care, and 911 if the person cannot respond (NIDDK, Low blood glucose). Ask your doctor or pharmacist before you add gymnema, and mention every supplement you use.

Read the full cautions on the side effects page and the interactions guide.

Verdict07

Is the gymnema in Payarmin enough to matter?

Probably not at a studied dose, and no one can confirm either way, because the amount is hidden.

Gymnema has a small, mild human record. In Payarmin it is one of 22 lines sharing 200 mg. Weigh that against the refund offer on the guarantee page.

FAQ08

Gymnema and Payarmin questions

What is gymnema sylvestre?

Gymnema sylvestre is a woody climbing plant whose leaves are dried and extracted for supplements. Payarmin lists "gymnema leaf extract" as its eighth blend line. The extract is sold for blood sugar and cravings, yet human evidence for either is limited.

Why is gymnema nicknamed the sugar destroyer?

The nickname comes from traditional use and marketing, and our sources do not test it. The NIH liver database describes gymnema as having lab and mild human glucose findings, not as destroying sugar. Treat the nickname as a sales phrase.

What are gymnemic acids?

Gymnemic acids are plant compounds often named as the active part of gymnema. The label does not list them and our sources do not measure them in Payarmin, so we cannot say how much the drops contain, if any.

Is there human research on gymnema and blood glucose?

Yes, but it is limited. Several trials showed mild drops in fasting plasma glucose, and the NIH says the overall effectiveness in treating diabetes has not been shown. Long-term and high-dose human effects are unstudied.

Can gymnema cause low blood sugar?

Lab and animal studies reported blood sugar lowering, but our main source does not describe low blood sugar as a risk in people. If you take insulin or another diabetes medicine, ask your doctor first, because added effects are possible.

Is gymnema safe to combine with diabetes medicine?

Our sources do not describe a gymnema drug interaction, which is not the same as proof of safety. Supplements can change how medicines act, so ask your doctor or pharmacist before adding it, and keep taking prescribed medicine.

How much gymnema is in Payarmin?

The label does not say. Because gymnema is eighth in a 200 mg blend, a serving holds at most 25 mg, and likely less. The usual studied dose is 400 mg three times a day.

Who wrote this09

Written and reviewed by

Written byThe Payarmin label deskGopayarmin, Payarmin U.S. shop

Pages built from the label, the sales page and linked NIH, FDA, CDC, FTC and peer-reviewed sources.

Medically reviewed byDr. Andres Palacio, MD, PhysicianRole: Medical reviewerReview date: October 19, 2026

Last updated . Read our editorial standards and how we check reviews. This website is run by Gopayarmin, a Payarmin U.S. shop, not by the manufacturer or the distributor. We earn money when you buy through our order links.

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